In the 1920s, there are several serious diseases that can kill people without having an antidote. Not only then, but also in these years, people all over the world are also facing COVID -19 where scientists are developing antidotes that can fight the virus. If we do not have these drugs, the number of deaths from the disease could be beyond our imagination, which is related to this unit's SOI "Historical turning points lead to significant changes in ideologies."